| Rank | Film | Weekend total | Weeks in release | Box office total |
| 1. | "Daredevil" | $45.03 million | 1 | $45 million |
| 2. | "How to Lose a Guy in 10 Days" | $20.71 million | 2 | $49.4 million |
| 3. | "Chicago" | $14.5 million | 8 | 82.6 million |
| 4. | "The Jungle Book 2" | $14.11 million | 1 | $14.1 million |
| 5. | "Shanghai Knights" | $12.80 million | 2 | $35.9 million |
| 6. | "The Recruit" | $7.28 million | 3 | $39.4 million |
| 7. | "Final Destination 2" | $6.24 million | 3 | $36.1 million |
| 8. | "Kangaroo Jack" | $5.04 million | 5 | $59 million |
| 9. | "Deliver Us From Eva" | $4.42 million | 2 | $12.3 million |
| 10. | "The Hours" | $3.86 million | 8 | $26.5 million |
Source: Nielsen EDI Inc.
