A team of MSU researchers might have found a crucial link between peptide levels in the brain and the escalation of Alzheimer’s disease.
For the project, professor Christina Chan and MSU alumna Hirosha Geekiyanage experimented with mice, which were genetically altered to be more likely to develop symptoms of the disease. The team injected a compound called L-cycloserine into the mice and later found it decreased levels of peptides that have been shown to lead to the plaques on the brain associated with Alzheimer’s.
Although the team has yet to perform a clinical trial, they plan to bring the experiment to a larger group of animals.
Among many types of dementia, Alzheimer’s is the most common, affecting millions of people every year. It is a degenerative disease and causes short- and long-term memory loss, mood swings, confusion and eventually death.